Evolution is often associated with long-lasting processes, which can not be observed directly. However, modern research methods and experiments demonstrate that particularly microorganisms are suitable for observing ‘evolution in fast motion’ and investigating evolutionary mechanisms within months or even weeks.
Due to high reproduction rates combined with short generation times, hundreds to thousands of generations of bacteria or viruses are available for direct comparison of genomes and phenotypic traits within a very short period of time.
Because of the short generation times the change of the organisms through mutation and selection becomes immediately visible. This is particularly the case when, for example, new pathogens like influenza viruses appear, when bacteria suddenly become resistant against antibiotics or when antiviral drugs become ineffective.
Complete documentation of the lineages allows for investigating and understanding the evolutionary dynamics and the genetic basis of adaptation.
Resistance to HIV - Information on the evolution of the resistance to HIV
Janina Jördens (corresponding author) & the ‘University of Münster’-Team (see credits)
PDF - 405 Koview
Janina Jördens (corresponding author) & the "University of Münster" - Team (see credits)
PDF - 456 Koview
Resistance to HIV - Sequence analysis of the "resistance-gene"
Janina Jördens (corresponding author), Marlen Puschmann, Jutta Lumer & the "University of Münster" - Team (see credits)
PDF - 2,59 Moview
Resistance to HIV - Sequence analysis of the "resistance-gene" as computer-based exercise
Janina Jördens (corresponding author) & the "University of Münster" - Team (see credits)
PDF - 1,04 Moview
Resistance to HIV – Application in the classroom
PDF - 396 Ko